Jonathan Carapetis Selected Research

Rheumatic Fever (Acute Articular Rheumatism)

1/2022	Population pharmacokinetic study of benzathine penicillin G administration in Indigenous children and young adults with rheumatic heart disease in the Northern Territory, Australia.
1/2021	High risk of early sub-therapeutic penicillin concentrations after intramuscular benzathine penicillin G injections in Ethiopian children and adults with rheumatic heart disease.
10/2020	Subcutaneous administration of benzathine benzylpenicillin G has favourable pharmacokinetic characteristics for the prevention of rheumatic heart disease compared with intramuscular injection: a randomized, crossover, population pharmacokinetic study in healthy adult volunteers.
1/2019	Severe adverse events following benzathine penicillin G injection for rheumatic heart disease prophylaxis: cardiac compromise more likely than anaphylaxis.
1/2019	A population pharmacokinetic study of benzathine benzylpenicillin G administration in children and adolescents with rheumatic heart disease: new insights for improved secondary prophylaxis strategies.
12/2018	Dysregulated IL-1β-GM-CSF Axis in Acute Rheumatic Fever That Is Limited by Hydroxychloroquine.
11/2017	Clinical development strategy for a candidate group A streptococcal vaccine.
10/2016	Preliminary consultation on preferred product characteristics of benzathine penicillin G for secondary prophylaxis of rheumatic fever.
1/2012	Rheumatic fever - identification, management and secondary prevention.
9/2006	Control of rheumatic heart disease in the Pacific region.

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Jonathan Carapetis Research Topics

Disease

12	Rheumatic Heart Disease (Rheumatic Heart Diseases) 01/2022 - 01/2012
10	Rheumatic Fever (Acute Articular Rheumatism) 01/2022 - 09/2006
7	Infections 01/2022 - 01/2011
4	Pharyngitis (Sore Throat) 07/2019 - 06/2015
3	Pain (Aches) 10/2020 - 01/2016
3	Communicable Diseases (Infectious Diseases) 04/2019 - 12/2012
2	Pneumococcal Infections 01/2022 - 01/2017
2	Otitis Media 01/2022 - 01/2020
2	Heart Failure 01/2022 - 01/2022
2	Gastroenteritis 11/2019 - 01/2018
2	Streptococcal Infections (Streptococcal Infection) 10/2016 - 11/2014
1	Disease Progression 01/2022
1	Hearing Loss (Hearing Impairment) 01/2022
1	Skin Diseases (Skin Disease) 04/2019
1	Anaphylaxis (Anaphylactic Shock) 01/2019
1	Myocarditis (Carditis) 12/2018
1	Autoimmune Diseases (Autoimmune Disease) 12/2018
1	Rheumatoid Arthritis 12/2018
1	Amebiasis (Amoebiasis) 01/2018
1	Impetigo (Impetigo Contagiosa) 11/2017
1	Undiagnosed Diseases 01/2017
1	Noncommunicable Diseases 05/2016
1	Human Influenza (Influenza) 01/2016
1	Diphtheria 01/2016
1	Inflammation (Inflammations) 01/2016
1	Myositis (Idiopathic Inflammatory Myopathies) 01/2016
1	Tetanus 01/2016
1	Whooping Cough (Pertussis) 01/2016
1	Tympanic Membrane Perforation 01/2015
1	Neoplasms (Cancer) 12/2012
1	Hypertension (High Blood Pressure) 12/2012
1	Sepsis (Septicemia) 01/2011
1	Scabies (Sarcoptic Mange) 05/2009
1	Emphysema 12/2002
1	Endocarditis 10/2002

Drug/Important Bio-Agent (IBA)

10	Penicillin G Benzathine (Benzathine Benzylpenicillin)FDA Link 01/2022 - 01/2016
10	Anti-Bacterial Agents (Antibiotics)IBA 07/2019 - 12/2002
6	VaccinesIBA 01/2018 - 01/2015
4	Penicillins (Penicillin)FDA Link 10/2021 - 10/2002
3	Proteins (Proteins, Gene)FDA Link 01/2022 - 01/2020
2	Conjugate VaccinesIBA 01/2022 - 01/2020
1	Immunoglobulin G (IgG)IBA 01/2022
1	Rotavirus VaccinesIBA 11/2019
1	RIX4414 vaccineIBA 11/2019
1	Immunoglobulin A (IgA)IBA 11/2019
1	Penicillin G (Benzylpenicillin)FDA LinkGeneric 01/2019
1	Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF)IBA 12/2018
1	Hydroxychloroquine (Plaquenil)FDA LinkGeneric 12/2018
1	CytokinesIBA 12/2018
1	nitazoxanide (NTZ)FDA Link 01/2018
1	Pneumococcal Vaccines (Pneumococcal Polysaccharide Vaccine)IBA 01/2017
1	Uridine Diphosphate (UDP)IBA 01/2017
1	Antiviral Agents (Antivirals)IBA 01/2016
1	Immunoglobulin E (IgE)IBA 01/2016
1	Influenza Vaccines (Influenza Vaccine)FDA Link 01/2016
1	Diphtheria-Tetanus-Pertussis Vaccine (DPT Vaccine)IBA 01/2016
1	Diphtheria-Tetanus-acellular Pertussis Vaccines (Tripedia)FDA Link 01/2016
1	Biomarkers (Surrogate Marker)IBA 08/2015
1	MicronutrientsIBA 12/2012
1	Tobacco Smoke Pollution (Passive Smoking)IBA 12/2012
1	ChlorhexidineIBA 01/2011
1	Permethrin (Ambush)FDA LinkGeneric 05/2009
1	CoagulaseIBA 10/2002

Therapy/Procedure

4	Secondary Prevention 10/2020 - 09/2006
3	Injections 01/2022 - 10/2020
2	Antibiotic Prophylaxis 01/2022 - 09/2006
2	Patient Readmission 01/2022 - 01/2022
2	Intramuscular Injections 10/2020 - 01/2016
2	Catheters 06/2015 - 01/2011
1	Therapeutics 08/2015
1	Central Venous Catheters 06/2015
1	Chemoprevention 11/2014
1	Ambulatory Care (Outpatient Care) 12/2012
1	Debridement 12/2002